Capillary Electrophoresis Market Size, Share, Growth & Industry Analysis, By Product (Instrument, Consumables, Software), By Mode (Capillary zone electrophoresis, Capillary gel electrophoresis, Capillary electrochromatography), By Application, By End Use, and Regional Analysis, 2024-2031

Market Definition

Capillary Electrophoresis (CE) is an analytical technique used to separate molecules, such as proteins, nucleic acids, and other charged species, based on their size and charge. In this process, the sample is injected into a narrow capillary tube, and an electric field is applied.

The molecules in the sample move at different speeds, depending on their charge and size, allowing them to be separated and analyzed. The market for CE includes products like CE instruments, consumables, and reagents, as well as applications in biotechnology, pharmaceuticals, and diagnostics.

The market encompasses areas such as drug development, clinical diagnostics, and research, driven by technological advancements, demand for precise molecular separation, and increasing applications in genomics and proteomics.

The report presents a comprehensive analysis of the key market drivers, emerging trends, and the competitive landscape, which are expected to determine the growth dynamics throughout the forecast period.

Capillary Electrophoresis Market Overview

The global capillary electrophoresis market size was valued at USD 321.5 million in 2023, which is estimated to be USD 337.5 million in 2024 and reach USD 512.9 million by 2031, growing at a CAGR of 6.16% from 2024 to 2031.

The growth in genetic research, driven by advancements in genomics and molecular biology, is a key driver of the market, aiding in DNA sequencing, mutation detection, and genetic analysis.

Major companies operating in the capillary electrophoresis industry are DH Life Sciences, LLC., Helena Laboratories Limited, QIAGEN, Thermo Fisher Scientific Inc., Agilent Technologies, Inc., SCIEX, Bio-Rad Laboratories, Inc., Bio-Techne, PerkinElmer, Sebia, Teledyne Technologies Incorporated, Thistle Scientific, Lumex Instruments, Promega Corporation, and Prince Technologies.

The market is expanding, due to the growing emphasis on personalized medicine and targeted therapies, particularly in cancer treatments. CE’s high resolution and sensitivity make it an ideal technique for identifying biomarkers and evaluating therapeutic efficacy, facilitating more precise treatment options.

With its ability to analyze complex biological samples, CE is becoming a vital tool in genomics, proteomics, and clinical diagnostics, due to its ability to analyze complex biological samples. It offers significant opportunities for advancements in drug development, disease diagnosis, and personalized healthcare solutions.

• In January 2025, research conducted by Universität Potsdam demonstrated that commercially available Capillary Gel Electrophoresis (CGE) systems efficiently separate and quantify plasmid DNA isoforms, outperforming traditional agarose gel electrophoresis (AGE). The study highlighted CGE's role in quantifying DNA-protein crosslinks, essential for understanding radiation-induced damage in cancer therapies, while minimizing manual errors and carcinogenic dye usage.

Key Highlights:

1. The capillary electrophoresis industry size was valued at USD 321.5 million in 2023.
2. The market is projected to grow at a CAGR of 6.16% from 2024 to 2031.
3. North America held a market share of 33.24% in 2023, with a valuation of USD 106.9 million.
4. The instrument segment garnered USD 123.6 million in revenue in 2023.
5. The capillary zone electrophoresis segment is expected to reach USD 214.0 million by 2031.
6. The nucleic acid analysis segment held a market share of 22.44% in 2023.
7. The pharmaceutical & biotechnology companies segment is anticipated to grow at a CAGR of 6.27% during the forecast period.
8. The market in Asia Pacific is anticipated to grow at a CAGR of 7.01% during the forecast period.

Market Driver

"Growth in Genetic Research"

Rapid advancements in genetic research, particularly in genomics and molecular biology, are significantly driving the capillary electrophoresis market. CE provides high-resolution, sensitive analysis for DNA sequencing, mutation detection, and genetic profiling.

Researchers are increasingly focusing on understanding genetic variations, hereditary diseases, and personalized medicine. This makes CE essential, as it provides accurate and reliable results.

The technology's ability to handle complex genetic samples efficiently, coupled with its rapid analysis capabilities, makes it a crucial tool in the expanding field of genetic research.

• In September 2024, Hitachi advanced CE technology to enhance cancer diagnosis by developing an affordable, high-sensitivity method for detecting multiple genetic mutations. This breakthrough supports the growing need for efficient genetic testing in personalized medicine and genomic research.

Market Challenge

"Complexity and Training Requirements"

A major challenge in the capillary electrophoresis market is the complexity of operating CE systems, which require specialized knowledge and extensive training. This can be a barrier for less experienced users and limit adoption, especially in smaller laboratories.

Companies are developing user-friendly interfaces, offering comprehensive training programs, and providing remote support to simplify system operations. Additionally, advancements in automation and data analysis software are reducing the need for manual intervention, making CE more accessible and efficient for a broader range of users.

Market Trend

"Label-free Techniques"

A noticeable trend in the CE market is the growing focus on label-free techniques, particularly capillary electrophoresis-mass spectrometry (CE-MS), for high-sensitivity glycan analysis. This approach eliminates the need for labels, which can introduce errors and sample loss.

Enabling direct analysis of native glycans preserves their structural integrity and provides more accurate, unbiased results. Such advances in technology are expected to significantly enhance glycan profiling, especially in challenging samples like single cells, offering more reliable data for disease research and diagnostics.

• In May 2024, researchers from Northeastern University published a study focusing on advancing single-cell glycomics. Their work, detailed in Nature Communications, presents a novel method for label-free N-glycan profiling of single mammalian cells using CE-MS.

Capillary Electrophoresis Market Report Snapshot

Market Segmentation:

• By Product (Instrument, Consumables, Software): The instrument segment earned USD 123.6 million in 2023, due to the increasing demand for high-precision, automated CE systems in research and clinical diagnostics.
• By Mode (Capillary zone electrophoresis, Capillary gel electrophoresis, Capillary electrochromatography): The capillary zone electrophoresis segment held 42.17% share of the market in 2023, due to its widespread use in efficient protein and nucleic acid separation.
• By Application (Nucleic acid analysis, Protein analysis, Genomic DNA, Plasmid DNA, Fragment Analysis, RNA/mRNA Analysis, Others): The nucleic acid analysis segment is projected to reach USD 114.9 million by 2031, owing to the increasing application of CE in genetic research and diagnostics.
• By End Use (Research Organizations & Institutes, Pharmaceutical & Biotechnology Companies, Clinical laboratories): The pharmaceutical & biotechnology companies segment is anticipated to register a CAGR of 6.27% during the forecast period, driven by the increasing demand for CE in drug development and quality control.

Capillary Electrophoresis Market Regional Analysis

Based on region, the market has been classified into North America, Europe, Asia Pacific, Middle East & Africa, and Latin America.

North America capillary electrophoresis market accounted for a share of around 33.24% in 2023, with a valuation of USD 106.9 million. North America continues to dominate the market, due to a robust healthcare infrastructure, significant investment in R&D, and a strong presence of key industry players.

The region benefits from advanced technological innovations, high government funding for scientific research, and stringent regulatory standards, which collectively drive market growth.

Additionally, established pharmaceutical and biotechnology sectors generate the demand for advanced analytical solutions, reinforcing North America’s leadership in the global market.

The capillary electrophoresis industry in Asia Pacific is poised for significant growth at a robust CAGR of 7.01% over the forecast period. Asia Pacific is emerging as the fastest-growing market for CE technologies, due to increasing investments in biotechnology, pharmaceuticals, and healthcare industries.

Rapid advancements in scientific research, coupled with a growing demand for high-resolution analytical solutions, are driving the adoption of CE in this region. The region's expanding healthcare infrastructure, coupled with rising R&D activities, is further fueling the demand for advanced CE systems, making it a key area for innovation and growth in the global market.

• In July 2024, Agilent introduced the ProteoAnalyzer at the Singapore Cell and Gene Therapy Pan Asia Summit. This advanced system combines high-resolution, automated CE with minimal sample consumption, aiding faster discoveries in protein analysis for the pharma and biopharma industries.

Regulatory Frameworks

• In India, the Medical Devices Rules, 2017 govern the classification, regulatory approval, and manufacturing of medical devices, including those using CE techniques, ensuring compliance with international standards for safety and quality.
• In the U.S., the FDA ensures public health by regulating the safety, efficacy, and security of medical devices, including those used in CE, and provides science-based health information to the public.
• In the EU, the Medical Devices Regulation (MDR) 2017/745 governs the marketing and use of medical devices, including those incorporating CE technology, while improving quality, safety, transparency, and market surveillance.

Competitive Landscape:

Companies in the capillary electrophoresis industry are focusing on enhancing automation, improving efficiency. They are integrating advanced technologies to offer higher resolution, reduced analysis time, and improved sample throughput.

Additionally, companies are prioritizing cost-effective solutions, streamlining workflows, and ensuring scalability to meet the growing demand for precise and reliable analytical results.

• In January 2024, Agilent Technologies introduced the ProteoAnalyzer system at the 23rd Annual PepTalk Conference in San Diego, California. This automated parallel CE system enhances protein analysis efficiency, providing faster and more accurate results with minimal sample consumption, benefiting industries like pharma, biotech, and academia.

List of Key Companies in Capillary Electrophoresis Market:

• DH Life Sciences, LLC.
• Helena Laboratories Limited
• QIAGEN
• Thermo Fisher Scientific Inc.
• Agilent Technologies, Inc.
• SCIEX
• Bio-Rad Laboratories, Inc.
• Bio-Techne
• PerkinElmer
• Sebia
• Teledyne Technologies Incorporated
• Thistle Scientific
• Lumex Instruments
• Promega Corporation
• Prince Technologies

Recent Developments (FDA Approval)

• In April 2024, Sebia announced FDA clearance for its CAPILLARYS 3 DBS devices, enhancing newborn hemoglobin disorder screening. This automated CE solution improves operational efficiency, throughput, and traceability, enabling laboratories to deliver accurate results with reduced manual intervention.